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Research Article

The Full Blood Count and D-Dimers of Patients Infected with COVID-19 at the Bamenda Treatment Center

Authors

  • Brain Tarawo Kwinji Department of Clinical Sciences, Faculty of Health Sciences, The University of Bamenda, Cameroon

    braintarawokwinji@gmail.com

  • Mbanya Dora Department of Clinical Sciences, Faculty of Health Sciences, The University of Bamenda, Cameroon
  • Samje Moses Department of Clinical Sciences, Faculty of Health Sciences, The University of Bamenda, Cameroon
  • Nadia Jacqueline Mandeng Department of Clinical Sciences, Faculty of Health Sciences, The University of Bamenda, Cameroon
  • Esoh Rene Tanwieh Department of Biotechnology and Food Technology, Punjabi University, Patiala, India https://orcid.org/0009-0006-6206-1257
  • Awizoba Hodabalo Department of Biotechnology and Food Technology, Punjabi University, Patiala, India
  • Laisin Mariette Vernyuy Department of Medical Microbiology and Parasitology, The university of Bamenda, Cameroon
  • Solomon Gyampoh School of Pharmaceutical Sciences, Lovely Professional University, Punjab-144401, India

Abstract

Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus-2, is an ongoing global pandemic affecting multiple organ systems, including the hematopoietic system, particularly in severe cases, which has been sparingly reported. This study aimed to describe the hematological profile (WBC count, lymphocyte count, hemoglobin, platelet count, and D-dimers) of COVID-19 patients and assess the impact of these changes on outcomes at the Bamenda Treatment Center. A cross-sectional retrospective study was conducted on medical records of eligible COVID-19 patients from April 20, 2020, to May 31, 2021, including cases with Full Blood Count or D-dimers but excluding those with confirmed death on arrival. Socio-demographic, clinical, and para-clinical data were analyzed using SPSS version 23, with significance set at p<0.05 and a 95% confidence interval. Of the 497 cases included, the mean age was 43.45±22.2 years, with a female predominance (male- to-female ratio of 1:1.5). Key findings included lymphocytopenia in 35.9% of participants and elevated D-dimers in 58.5%, with higher median D-dimers observed among non-survivors (Median: 1470.69, IQR: 5020.2) and those requiring supplemental oxygen (Median: 1289.75; IQR: 321.42–5341.67). Additionally, hospitalized patients with low platelet counts (83.3%) had significantly lower mean platelet counts than those quarantined at home (16.7%) (p<0.001). These findings highlight the significance of hematological changes among COVID-19 patients, particularly elevated D-dimers and lymphocytopenia, and underscore the need to monitor full blood count and D-dimers during initial consultations to enhance patient management and risk stratification.

Keywords:

Anemia Coronavirus COVID-19 Hematology Lymphocytopenia Thrombocytopenia

Article information

Journal

Journal of Medical Science, Biology, and Chemistry

Volume (Issue)

1(2), (2024)

Pages

9-35

Published

24-12-2024

How to Cite

Kwinji, B. T., Dora, M., Moses, S., Mandeng, N. J., Tanwieh, E. R., Hodabalo, A., Vernyuy, L. M., & Gyampoh, S. (2024). The Full Blood Count and D-Dimers of Patients Infected with COVID-19 at the Bamenda Treatment Center. Journal of Medical Science, Biology, and Chemistry, 1(2), 9-35. https://doi.org/10.69739/jmsbc.v1i2.180

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